Semaglutide tells your brain you’re full — even when you haven’t eaten much. It slows digestion, crushes cravings, and makes you naturally eat less without feeling deprived. This is the same active ingredient as Ozempic and Wegovy. Clinical trials show average weight loss of 15% of total body weight.

Tirzepatide targets two hunger hormones simultaneously — GLP-1 and GIP. Two brakes on your appetite instead of one. Clinical trials showed people losing up to 22% of body weight, plus improvements in blood sugar and energy.